~/talk

Distributed Visualization for Genomic Analysis

Talkat Data By the Bay 2016 · 2016-05-16..05-20· [data-visualization]
links:none on file
name:Eric Tu
links:none on file
slides:none on file

Mango is a distributed genome browser that materializes requested regions from persistent storage (BAM/VCF or Apache Parquet via ADAM) into memory organized as an interval RDD backed by interval trees, enabling fast two‑dimensional range queries over ~2,500-sample variant data (terabytes). It uses data tiling and layered summaries to show raw reads up to sliding-window aggregates, runs on Spark for horizontal scaling, prefetches neighbor regions, and approaches interactive latency (~500 ms) once cluster cores exceed single-node limits; source on GitHub.

AI-written summary · about

  1. 0:00Introduction to team
  2. 1:18What is genomic analysis
  3. 2:23From sequencing to variants
  4. 4:52Challenge of big genomic data
  5. 6:40Ideal genome browser goals
  6. 7:45Introducing Mango browser
  7. 11:17Optimizing for low latency
  8. 16:16Local performance comparison
  9. 17:18Scaling with distributed data
  10. 18:24Future improvements and Q&A
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