The Microbiome

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Claims that the human microbiome contains trillions of microbes and a metagenome more than 100 fold greater than the human genome are supported by culture-independent surveys using 16 S RNA sequenzing and metagenomics. Diversity, richness and abundance determine health or dysbiosis, which the talk links to diabetes, obesity, fatty liver, cardiovascular disease and mood via the brain–gut axis. Metabolites can inactivate drugs. Therapeutic moves include probiotics, antibiotics and established fecal microbiota transplantation for refractory Clostridium difficile, delivered by colonoscopic instillation of stool slurry.

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" chapters (10)

1. 0:00Human microbiome intro
2. 2:18What is the microbiome
3. 5:16Factors affecting diversity
4. 7:54Microbiome development
5. 9:45Aging microbiome health
6. 10:47Microbiome and colorectal cancer
7. 12:41Diet, brain, and mental health
8. 13:45Diseases from microbiome disruption
9. 14:28Therapies and transplants
10. 15:33Key takeaways and future