~/talk

Building a Virtual Biology Platform on Ray

Talkat Ray Summit 2026 · 2026-08-24..08-26· [machine-learning, distributed-systems]
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slides:none on file

Recursion runs a virtual biology platform on Ray and Anyscale over a 60 PB dataset with 40 PB proprietary, claiming to cut cloud spend while improving reliability. They replace brittle Kubernetes and Prefect jobs with Ray array tasks that do concurrent download + inferencing and retry at task granularity, add plate-level GPU cost metrics, and route jobs across GCP and on‑prem BioHive GPUs (H100/A100 pool) using a priority-aware router called cake. Migration takes about a year and yields better observability, portability, and cost control.

AI-written summary · about

  1. 0:00Introduction to virtual biology
  2. 2:00Recursion’s platform and mission
  3. 5:16Four-step drug discovery loop
  4. 6:22Phenomics pipeline challenges
  5. 10:40Requirements for new platform
  6. 12:51Why Ray and Anyscale
  7. 15:40Anyscale as infrastructure layer
  8. 16:01Phenomics pipeline today
  9. 19:12Portability across clusters
  10. 20:15Compute routing with CAKE
  11. 21:19Transcriptomics on Ray
  12. 22:47Predictive chemistry workloads
  13. 24:15Virtual cell simulations
  14. 27:04Building a unified platform
  15. 28:07Q&A session
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