“KubeGene” a Genome Sequencing Workflow Management Framework
summary
KubeGene is an open source workflow framework built on Kubernetes that schedules genome pipelines across hundreds of nodes to manage TB/PB of data; it runs WGS/WES, liquid biopsy and single‑cell pipelines (GATK supported), launches containers per step, and preserves legacy HPC commands via direct shell commands. One human genome yields ~200 GB per sample and KubeGene adds dynamic concurrency, autoscaling, namespace/file authorization, and a Kubernetes job engine; adoption and contributors already include Huawei, Filea Next Omics and partners.
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chapters (7)
- 0:00Introduction
- 4:55Gene Sequencing
- 12:43Human Genome Sequencing
- 14:32Advantages of Container
- 18:25Workflow
- 27:03Framework
- 30:08Project
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